Chinese Journal of Tissue Engineering Research ›› 2014, Vol. 18 ›› Issue (9): 1331-1336.doi: 10.3969/j.issn.2095-4344.2014.09.004

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High risk factors in 128 elderly patients undergoing hip replacement

Zhang Ke-yun1, Yu Li-ming1, Zhang Xu-hua1, Lin Xin1, Zhang Ren-ming1, Liu Jun1, Chen Chao2, Wang Jian-chao2   

  1. 1 Department of Orthopedics, Affiliated Hospital of Huaihua Medical College, i.e., Huaihua Municipal Third People’s Hospital, Huaihua 418000, Hunan Province, China; 2 Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430032, Hubei Province, China
  • Online:2014-02-26 Published:2014-02-26
  • Contact: Wang Jian-chao, Chief physician, Associate professor, Master’s supervisor, Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430032, Hubei Province, China
  • About author:Zhang Ke-yun, Associate chief physician, Department of Orthopedics, Affiliated Hospital of Huaihua Medical College, i.e., Huaihua Municipal Third People’s Hospital, Huaihua 418000, Hunan Province, China

Abstract:

BACKGROUND: Deep vein thrombosis after hip replacement has a high incidence rate. Moreover, deep vein thrombosis can induce pulmonary embolism that can endanger patients’ life and dysfunction of distant deep vein. The appearance of deep vein thrombosis is a great obstacle for the gradually increased hip replacement.
OBJECTIVE: To observe the occurrence of deep vein thrombosis of lower limb after total hip replacement in elderly patients, and to screen the risk factors for the occurrence of deep vein thrombosis of lower limbs.
METHODS: Clinical data of 128 elderly patients with hip replacement were analyzed retrospectively. All patients were examined with color Doppler ultrasound in double lower limbs at 1 day before replacement and 7 days after replacement. Multifactor unconditional logistic analysis was conducted on clinical related factors and the formation of lower limb deep vein thrombosis.
RESULTS AND CONCLUSION: At 7 days after the operation, 16 patients affected deep vein thrombosis of lower limb. The factors for deep vein thrombosis contained female, general anesthesia, bilateral hip replacement and the application of bone cement (P < 0.05). The risk for deep vein thrombosis after total hip replacement significantly increased in elderly patients aged over 70 years. Multifactor unconditional logistic analysis exhibited that the multiple risks of sex, obesity and the use of bone cement in elderly patients with deep vein thrombosis increased to 11.398, 3.109 and 8.925. The patients with a blood type O at the age of over 70 years experienced a decreased risk for deep vein thrombosis after total hip replacement. The occurrence of deep vein thrombosis decreased to 0.186 times after replacement. Blood type O could be considered as a protective factor for the occurrence of deep vein thrombosis.


中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程


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Key words: arthroplasty, replacement, hip, venous thrombosis, aged, risk factors

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